ASK-ing EMT not to spread cancer
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چکیده
منابع مشابه
ASK-ing EMT not to spread cancer.
G lobal communication by the epithelial cell layer is maintained through gap junctional complexes, separated from adjacent tissues by a basal lamina. Mesenchymal cells are loosely organized in a three-dimensional extracellular matrix, comprising connective tissue adjacent to the stroma. Conversion of epithelial cells to mesenhymal cells involves profound phenotypic changes, including loss of ce...
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“To be, or not to be? That is the question.” William Shakespeare, The Tragedy of Hamlet, Prince of Denmark (1599-1602). Viral infection triggers host defense mechanisms that include the production of type I interferon (IFN) and the induction of apoptosis. Type I IFN, such as IFN-α and IFN-β, establishes the antiviral state to inhibits viral replication within infected cells, whereas apoptosis o...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2010
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0914721107